Background: We set out in this study to demonstrate the adverse effect profile of methotrexate when used in the treatment of rheumatoid arthritis (RA) and psoriatic arthritis (PsA) in a district ...

Methotrexate (MTX) remains a cornerstone in the treatment of rheumatoid arthritis, despite the advent of newer biologic therapies, because of its long-term efficacy and safety. However ...

Methotrexate is the first-line treatment for most people with moderate to severe rheumatoid arthritis (RA). Some medications, however, can interact with methotrexate and cause adverse effects. This ...

Introduction We aimed to compare the proportions of patients with newly diagnosed psoriatic arthritis (PsA) and rheumatoid arthritis (RA) remaining on methotrexate (regardless of other ...

Objective To compare the effects of interleukin-6 (IL-6) receptor and tumour necrosis factor inhibition on inducing repair of existing bone erosions in patients with very early rheumatoid arthritis ...

Immunogenicity of adalimumab could impair important treatment outcome parameters in patients with rheumatoid arthritis (RA). Patients who developed antiadalimumab ... severe disease and less often ...

While biologic treatments do not cure rheumatoid arthritis (RA), they can slow ... may give you a biologic alongside or in place of methotrexate, an anti-rheumatic. Taking a biologic with ...

Have you ever felt hand pain that makes simple tasks like buttoning a shirt, opening a jar, or shaking hands almost ...

If you take medications to treat rheumatoid arthritis, smoking can interfere with their activity and make them less effective. This includes such foundational medications as methotrexate and newer TNF ...

Higher MTX-PG concentrations were associated with improved disease activity among patients with RA receiving MTX therapy, though they were also linked to hepatotoxicity.

Rates of heart failure with preserved ejection fraction (HFpEF) were doubled in patients with rheumatoid arthritis (RA) ...

Rheumatoid arthritis is an autoimmune disease that is characterized by inflammation of the joints and the subsequent destruction of cartilage and erosion of the bone. Patients with rheumatoid ...