The drug, an oral Mas-related G protein-coupled receptor X2 (MRGPRX2) antagonist, was designed to inhibit mast cell degranulation to ease CSU symptoms. Celldex's shares saw a significant increase ...
One of the ways SCFAs interact with our immune system is by mediating the activation of mast cells (MCs). These white blood cells are loaded with small sacs called "granules," which are full of ...