近年来，纳米材料与生物分子的相互作用受到广泛关注。研究表明，纳米材料接触体液后会与生物分子相互作用，形成以 低密度脂蛋白（LDL） 为主的生物分子冠。脂蛋白吸附可延长纳米材料的 血液循环时间 ...

Lipid abnormalities play a critical role in ... LDL particles in excess infiltrate the artery and are retained in the intima. Macrophage uptake of modified LDL particles leads to cell accumulation ...

Parameters of systemic metabolism, hepatic steatosis and AS were evaluated. Human THP-1 macrophages were used to investigate the effect of 2PY on oleic acid-induced foam cell formation. Lipidomic and ...

Recently, macrophage lipid loading has been shown to potentiate inflammatory activation ... These data suggest that therapeutic approaches targeting lipid metabolism may have an outsized benefit for ...

Department of Physiology, Harold Hamm Diabetes Center, The University of Oklahoma Health Science Center, Oklahoma City, United States ...

Metabolism is the process by which your body turns food into energy through chemical reactions in your cells. Your metabolic rate is a measurement of how many calories (units of energy) your body ...

This study performed in-depth multi-omics analyses, comprising a total of 772 metabolites (including lipids, polar metabolites ... Specific TAGs might be functionally associated with pro-resolving ...

English Edition Medscape English Deutsch Español Français Português UK New Univadis ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Lipid droplets (LDs) serve as crucial hubs for ...

Notably, a deficiency of FABP4 in murine macrophages significantly reduces LA-induced lipid metabolism. Therefore, our findings suggest FABP4 as a crucial lipid messenger that facilitates unsaturated ...

Lipids play an important role in human nutrition. Although adequate lipid consumption is necessary for an optimal functioning of the human body, overconsumption of saturated fatty acids can lead to ...

A currently favored paradigm for obesity-associated metabolic dysfunction is that chronic macronutrient and/or lipid overload ... report on the infiltration of macrophages into adipose tissue ...