While most pharma companies have exited the antibiotics area, Japanese drugmaker Shionogi has stuck with it and has just expanded its pipeline with a deal to buy US biotech Qpex Biopharma.

BLIs are designed to overcome a key resistance mechanism that allows pathogens to protect themselves from cefepime and other antibiotics in the beta-lactam class and have been used to restore acti ...

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Center have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.jafc.4c07028. Synthetic routes of two magnetic probes; characterization ...

Insert length between 800 and 3000 bp. ‡‡ One clone was resistant to all three antibiotic classes in a secondary screen. The generic term 'antibiotic' is used to denote any class of organic ...

Rutgers Health research has uncovered why a relatively new antibiotic for tuberculosis (TB) works against multidrug-resistant strains, potentially inspiring improved treatments and drug ...

Conventionally, S. aureus infections were treated with β-lactam antibiotics. Over time, the pathogen developed resistance to the β-lactamase, which led to the introduction of methicillin ...

MRSA's double defense against antibiotics Date: October 31, 2024 Source: University of Sheffield Summary: Scientists have discovered the mechanism which allows the superbug Methicillin Resistant ...

The new research, led by the University of Sheffield, reveals MRSA has a double defense mechanism against antibiotics—this new insight offers hope in treating the life-threatening superbug and ...