Researchers described a promising new approach for using gene therapy to treat sickle cell disease in the journal Human Gene ...

Cyclosporin H boosts a new lentivirus-delivered gene therapy with enhanced anti-sickling properties in blood stem cells from ...

An exemplar case is Gracell Therapeutics who devised the 22–36 h F-CAR manufacture process of T-cell enrichment and activation; lentiviral transduction in IL-2-supplemented culture medium; and harvest ...

Here, we used deep full-length single-cell RNA-sequencing to distinguish post-mitotic cone and rod developmental states and cone-specific features that contribute to retinoblastomagenesis. The ...

This process requires the absence of the nuclear ... various transgenes in bi- or multi-cistronic retroviral vectors. Lentiviral self-inactivating vectors are the retroviral vectors with the ...