Kinases are enzymes that catalyze the addition of a phosphate group (PO43−) to substrates, usually proteins. The phosphate generally comes from adenosine triphosphate (ATP). Kinases and ...

Cell-cycle progression in eukaryotic cells, including the decision to initiate DNA replication, is driven by cyclin-dependent kinases (CDKs). The catalytic subunit of CDK is only active as a ...