Emmons (HWE) reaction is commonly used in organic chemistry to synthesize conjugated aldehydes. However, traditional HWE reaction methods sometimes have inconsistent (E)- and (Z)-selectivity, and ...
cations, reaction concentrations, and temperatures on the reactivity and selectivity of the Weinreb amide–type HWE reaction. They discovered that using isopropyl magnesium bromide (i PrMgBr ...
Institute of Organic Chemistry and Biochemistry of the Academy of Sciences, Flemingovo Nám. 2, Prague 16610, Czech Republic University of Chemistry and Technology Prague, Technická 5, Prague 16628, ...
This study presents an important investigation of water coordination in a specific kinase family with a focus on the regulation of osmosensing protein kinases. X-ray crystallographic approaches ...
Introduction: Antimicrobial-resistant pathogens are an ongoing threat to human and animal health. According to the World Health Organization (WHO), colistin is considered the last resort antibiotic ...
The study presents important findings that reveal SEPHS2 and VPS37C as new potential drug targets for dasatinib and hydroxychloroquine respectively in addition to confirming known targets of these ...