A high-resolution spatial multiomics approach reveals how a specific subpopulation of myofibroblasts drives scar formation ...
Most interesting, however, was the finding that this interaction required the β1 integrin subunit. The use of integrin subunit-blocking antibodies considerably blocked the adhesion of tumor cells ...
Taken together, these experiments demonstrate that RAB25 interacts directly with the β1 subunit of α5β1 to maintain a pool of actively cycling α5β1 integrin at the tips of extending pseudopodia.