A full-size IgG antibody is a Y-shaped complex of two identical light chains, each with a variable and constant domain, and two heavy chains, each with one variable and three constant domains.
Antibody humanization involves modifying antibodies ... Nanobodies are VHH segments derived from camelid antibodies. These single-domain antibodies are considerably smaller than traditional ...
Transforming the landscape of drug discovery with next-gen capabilities in obesity research, small molecule and antibody design, antibody-drug conjugate development, and interactive AI AlpaMeld Logo ...
Many challenges will have to be faced in the next decade to bring more efficient and affordable antibody-based drugs to the clinic. Here, we discuss strategies to select the best therapeutic ...