2024年10月30日，来自美国西奈山伊坎医学院的Brian D. Brown和Alessia Baccarini研究团队在Cell上发表题为“Ovarian cancer-derived IL ... 而大多数T细胞亚群，包括耗竭的CD8 T细胞，在Il4敲除肿瘤中富集，并出现富含B细胞和T细胞的淋巴细胞聚集，类似三级淋巴结构。

The past few years have seen a surge of interest in B cell depletion therapy for patients with rheumatoid arthritis. This paper outlines the possible mechanism(s) by which B cell depletion therapy ...

Dec. 2, 2024 — Eating a diet with a higher ratio of plant-based protein to animal-based protein may reduce the risk of cardiovascular disease (CVD) and coronary heart disease (CHD), according to ...

We conducted a phase 1b–2 multicenter study of obe-cel in adults (≥18 years of age) with relapsed or refractory B-cell acute lymphoblastic leukemia (ALL). The main cohort, cohort 2A ...

Nov. 26, 2024 — Scientists have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular 'bridge' complex demonstrate a new ...

Methods Inflammatory cells from 12 RA patients were sorted into CD4 and CD8 T cells, B cells, macrophages and neutrophils. mRNA expression for 41 cytokines was determined by real-time PCR using ...

Obe-cel is the first FDA-approved CAR T-cell therapy for B-ALL without a REMS requirement, based on the FELIX trial's positive outcomes. The FELIX trial reported a 63% complete remission rate ...

A precancerous cell is a cell with certain abnormalities that makes it more likely to become cancerous. These abnormalities don't mean that it will become cancer—in fact, most don't—but the diagnosis ...

Vitamin B complex is a group of B vitamins that play a role in your body’s functions, including cardiovascular and cell health. You typically get these vitamins from a nutritious diet.

Vitamin B complex has benefits for metabolism, energy production, and red blood cell development. You need B vitamins to prevent deficiency and certain health issues. Several foods, like meat ...