Type 2 diabetes (T2D) and obesity (OB) are associated with chronic low-grade inflammation and increased fracture risk. In vitro studies showed that inflammation induces bone erosion and inhibits bone ...

Since signalling by TNFα and IL-1β is not exclusively mediated by the endosomal pathway, inhibition by HCQ is most likely incomplete and the effects of HCQ, for example, on signalling by TNFα will be ...

Belgian biopharma company UCB is bringing up the rear of the IL-17 inhibitor category with its bimekizumab drug, so is celebrating new late-stage data showing superiority to the class leader.

This study presents important findings on the role of CXXC-finger protein 1 in regulatory T cell gene regulation and function. The evidence supporting the authors' claims is solid, with mostly ...

InnoCare Pharma (HKEX: 09969; SSE: 688428), a leading biopharmaceutical company focusing on the treatment of cancer and autoimmune diseases, today announced that the first subject has been dosed in ...

belle.shiga-med.ac.jp Background and aim: Interleukin (IL) 17 is a cytokine which exerts strong proinflammatory activities. In this study we evaluated changes in IL-17 expression in the inflamed ...

慢性支气管炎（CB ）是一种十分常见的慢性炎症，集中发作于气管、支气管黏膜及周围组织。主要症状为咳嗽、咯痰或伴有喘息［1 ］，好发于老年群体，起病较缓，但病程较长，反复发作，病情可逐渐加重，严重者可逐步发展为慢性阻塞性肺疾病，甚至慢性肺源性心脏病［2 ...

Here’s how it works. That final phone may steal much of the attention, but it’s the iPhone 17 Pro Max that will probably have the most impressive specs. And while we’re not expecting it to ...

Emmanuel Caeymaex, Executive Vice President and Chief Commercial Officer, UCB, called the FDA’s decision a “milestone” for the company in its mission to address unmet needs across a range of IL-17 ...