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Science DNA breaks are toxic lesions for the cell. In order to repair these breaks, it is necessary, starting from the break ends, to find a homologous sequence within the vastness of the genome. In ...

Eisbach Bio's innovative approach focuses on exploiting the unique genetic vulnerabilities present in solid tumors with deficiencies in certain DNA repair pathways. Eisbach’s proprietary ALLOS ...

Clone with Python! Data structures for double stranded DNA & simulation of homologous recombination, Gibson assembly, cut & paste cloning.

On International Men's Day, the Clinical Trials Arena team investigates three therapies being investigated in prostate cancer ...

Their reliability, scalability, and established regulatory pathways further underscore their importance in the ...

Two of the three candidates (XIN5104 and XIN5789) are in preparation for clinical trials in solid tumours with homologous recombination ... the DNA damage repair pathway in treating cancer and ...

Department of Molecular Biology, Kyushu University Graduate School of Pharmaceutical Sciences, Fukuoka, Japan ...

Summary and Introduction Clinical Application—Disease Entities Theoretical Framework for Therapy−The 'Steel Paradigm' Conclusion References Theoretical Framework for Therapy−The 'Steel ...