Among other nucleophilic residues that could be in principle used for the design of covalent drugs, histidine (His) has not been given proper attention despite being in principle an attractive residue ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Histidine modifications of proteins are broadly based on chemical methods triggering N ...

Contrary to the belief that the path to sustainable development is increasingly out of reach, the results show that humankind has a variety of pathways ... and avert further degradation of the ...

Using experiments in microfluidic devices and through measurements of motility and gene expression, the authors offer convincing evidence that the degradation products of polysaccharide digestion can ...

A major focus is the degradation of the lands of the Earth. This means the actions that are causing the land's overall health to decline, become less fertile, store less carbon and be able to ...

Solar pathway lights are a favorite garden light among homeowners, and with good reason. They don’t require outlets, they’re eco-friendly and energy-efficient, plus, thanks to the array of ...

Overproduced yeast ribosomal protein (RP) Rpl26 fails to assemble into ribosomes and is degraded in the nucleus/nucleolus by a ubiquitin-proteasome system quality control pathway comprising the E2 ...