In that cycle, RuBP plus CO 2 produces two molecules of a compound called 3-phosphoglyceric acid (PGA). The ATP produced in ...

This model is based on a critical observation we made: diabetes in animals and patients, and hyperglycemia in cells, all decrease the activity of the key glycolytic enzyme glyceraldehyde-3 ...

Chronic exposure to hyperglycemia can lead to cellular dysfunction that may become irreversible over time, a process that is termed glucose toxicity. Our perspective about glucose toxicity as it ...