Gene regulation in immune cells refers to the mechanisms used by immune cells to increase or decrease the production of specific gene products. Here, Fry and colleagues examine the impact of ...

Upon deletion of the ALAS2 gene, the researchers subsequently observed classic symptoms of XLSA like anemia and enlargement of the spleen. The model also allowed the researchers to note features ...

Upon deletion of the ALAS2 gene, the researchers subsequently observed classic symptoms of XLSA like anemia and enlargement of the spleen. The model also allowed the researchers to note features of ...

The course focuses on current understanding of the structure and function of eukaryotic transcription factors. Topics covered are: promoters, RNA polymerase II, general transcription factors and ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

An exploration of the unanswered questions in how the molecular chaperone Hsp90 supports protein homeostasis, and how single-molecule techniques could drive future breakthroughs in answering them.

The new year will bring freshmen members of Congress and President-elect Donald Trump, who made big promises to the industry during his campaign.

Gene therapy is a disruptive technology which heralds a new chapter in the way that rare genetic diseases will be treated. But it isn’t just a new way to transform clinical outcomes.

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23, 2024 — A new gene editing tool that helps cellular machinery ... the formation of amyloid-beta plaque precursors in a mouse model of ...