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G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...
This interesting study presents valuable information on how human cytomegalovirus (HCMV) infection disrupts the activity of the TEAD1 transcription factor, leading to widespread chromatin alterations.
"Our study reveals a new pathway of temperature perception in ... Under normal conditions, COLD6 interacts with rice G-protein α subunit (RGA1) at the plasma membrane. Under chilling conditions ...
This selective interaction might make it an intriguing candidate for investigating cellular signaling pathways, where precision is critical. While the exact mechanisms through which PE-22-28 may ...
Active ERK phosphorylates numerous substrates, both nuclear and cytoplasmic, to affect gene transcription, protein translation, cell growth, proliferation and survival. Both RTKs and Ras also activate ...