(2004) Prospective, multicenter, DB, RCT examining 0.5% 5-FU (Carac) once daily vs vehicle cream once daily for ... highlighted the importance of topical 5-fluorouracil in treatment of the lesions.

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We concluded that for closed wounds, the use of topical neomycin postoperatively should be avoided. White petrolatum is an efficacious and cost-effective alternative for closed wounds. For open ...

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