Erythroblasts possess unique characteristics as they undergo differentiation from hematopoietic stem cells. During terminal erythropoiesis, these cells incorporate large amounts of iron in order to ...
The study is important to show the role of MED26 in red cell formation. Linking transcription pausing with erythropoiesis is a key discovery. The data are solid although there are still spaces to ...
Vadadustat for symptomatic anaemia associated with chronic kidney disease: missed opportunity Important patient-relevant outcomes were not recorded in the two studies conducted by the drug ...
Here the authors characterise bone marrow cells from PRCA patients by single cell sequencing showing hyperactive CD8 + T cells, impaired erythropoiesis, increase of MHC-I proteins and antigen ...