Enzymes catalyze nearly all of the chemical reactions that occur in biological systems. Enzymes are generally proteins but also include catalytic DNA and catalytic RNA. As effective biological ...
By decomposing the modeling of enzyme-substrate interactions into a two-stage process, MESI incorporates two conditional networks that respectively emphasize enzymatic reaction specificity and crucial ...
We can provide clear, chemical rationale for why enzymes that catalyze completely distinct reactions share sequence and structural homology (for example, Fig. 2), or why the ribosome is a ribozyme ...
State Key Laboratory of Bioreactor Engineering, Shanghai Collaborative Innovation Center for Biomanufacturing, East China University of Science and Technology, Shanghai 200237, China State Key ...
Biocatalysis is a process that uses enzymes as natural catalysts to carry out chemical reactions. Scientists at The University of Manchester and AstraZeneca have developed a new biocatalytic ...
In mice, inhibiting protein S-palmitoylation Counteracted accumulation of harmful proteins in neurons and delayed onset and progression of cognitive decline.