Treatment-resistant depression (TRD) occurs when major depressive disorder (MDD) treatment does not work. There is no official definition or set criteria for TRD, but the measure often used is an ...
Learn more about anxiety medications. The first line of treatment for depression is antidepressant medication. Some people may need a combination of drugs to best manage their condition.
Depression is considered treatment-resistant after multiple types of medications, used singly and in various combinations, fail to significantly improve symptoms or create side effects that are ...