Nucleic acid therapeutics are based on nucleic ... where specific inhibition of the function of a particular gene involved in disease is thought to be therapeutically desirable.
Rather than influencing downstream molecules, the way conventional drugs might block the binding of proteins, nucleic acid drugs can tackle the genetic roots of disease. “We can basically drug ...
It breaks down fats into fatty acids, which can then be absorbed by the digestive tract. Bile is made in the liver and stored in the gallbladder, a sort of storage sac organ attached to the underside ...
Acquired Immunodeficiency Syndrome (AIDS) is a chronic, potentially life-threatening condition caused by the Human Immunodeficiency Virus (HIV). By damaging the ...
Acid peptic diseases result from distinctive but overlapping pathogenic mechanisms that typically involve acid effects on diminished mucosal defense. Conditions such as acid reflux, damage the ...
zju.edu.cn, zyyyych{at}zju.edu.cn Objective Accumulation of free fatty acids (FFAs) in hepatocytes induces lipotoxicity, leading to non-alcoholic fatty liver disease (NAFLD). This study aimed to ...
The performance metrics showed significant uplift across these tasks, with AlphaFold 3 achieving accuracy levels that outpaced traditional docking and nucleic acid prediction tools. With improved ...
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.