Nature Cell Biology - During development, stem and progenitor cells gradually commit to differentiation pathways. Cell fate decisions are regulated by differentiation factors, which activate ...

These are found in a mature organism. Their function is to replenish all of the types of (differentiated) cells found in that specific tissue. Tissue stem cells are multipotent. This means that ...

When cells express specific genes that characterise a certain type of cell we say that a cell has become differentiated. Once a cell becomes differentiated it only expresses the genes that produce ...

Synthetic biology is the design and construction ... synthetic cells is that they must become desensitized to certain differentiation signals that are received after their initial response and ...

Understanding the regulatory mechanisms that define and ultimately restrict cell fate has important implications for regenerative medicine, cancer research, and developmental biology. To meet this ...

By combining various gene and cellular biology techniques ... They also explored how neuropeptides ensure optimal T cell differentiation and drive robust antiviral responses.