Corticosteroid therapy must be tapered because of its interactions with the hypothalamic-pituitary-adrenocortical (HPA) axis. The hypothalamus secretes corticotropin releasing factor, which acts ...
Dexamethasone phosphate (as sodium); 4mg/mL, 10mg/mL; soln for IV or IM inj; contains sulfites. Potentiated by CYP3A4 inhibitors (eg, ketoconazole, macrolides), cyclosporine, estrogens ...