The composer would outlive his doctor by nearly two decades, yet close to two centuries after Beethoven's death a team of researchers set out to fulfill his testament in ways he would never have ...
Poly(ADP-ribose) polymerase 1 (PARP1) is one of the first responders to DNA damage and plays crucial roles in recruiting DNA repair proteins through its activity – poly(ADP-ribosyl)ation (PARylation).