The genetic connections between DNA repair pathways and human cancer predisposition have fueled interest in the proteins that recognize and repair specific sites of DNA damage. The repair enzymes are ...

However, the cell’s DNA damage response is hugely complex and has many moving and interconnected parts ... We need to understand how it works on a mechanistic level and why each part can contribute to ...

Fever increases immune cell metabolism, proliferation, and activity, but it also causes mitochondrial stress, DNA damage, and ...

然而，SMARCA5在前列腺癌中的调控机制在很大程度上尚未被阐明。 11月5日，南昌大学傅斌教授研究团队在期刊《Cell Death&Disease》上发表了研究论文，题为“USP3 promotes DNA damage response and ...

We provided the first conclusive evidence that the basic cause of cancer is damage to DNA. The discovery changed scientific opinion dramatically and marked a turning point for cancer research. Until ...

New research from the Kind Group sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates ...

A multi-institutional team of researchers, led by Georgia Tech's Francesca Storici, has discovered a previously unknown role ...

DNA repair: A look inside the cell's 'repair café' Date: November 21, 2024 Source: Hubrecht Institute Summary: New research sheds light on how cells repair damaged DNA. For the first time, the ...

Usually, excessive DNA damage triggers cell death. However, TNBC has a propensity to accumulate DNA damage without consequence, making it resilient to conventional treatments. The study helps ...