Understanding how deletion mutations in mitochondrial DNA contribute to aging can help delay age-related decline in ...

This study provides important insights into the regulation of a retained intron in the mRNA coding for OGT, a process known to be regulated by the O-GlcNAc cycling system, and highlights the ...

Research utilizing AI tool AlphaFold has revealed a new protein complex that initiates the fertilization process between ...

Revealing the circuits driving protein gradients. Key cellular processes, such as cell differentiation, rely on protein gradients, i.e. the uneven distribution of proteins within ...

The experimental therapy Bravyl significantly reduced the spread of toxic TDP-43 protein clumps in a cell model of ALS.

Now, scientists have discovered that human cells are home to their own hidden superheroes, secretly helping us to fight off a ...

Mitochondria and cytoplasm separation, genome extraction and qPCR were used to detect mitochondrial DNA (mtDNA) leakage. Mitochondria ultrastructure was detected by transmission electron microscopy.

Insights into protein synthesis processes in prokaryotes and eukaryotes are crucial for advancements in genetics, ...

Here, we show that TPR, a protein of the nuclear pore complex basket required for heterochromatin re ... immune signalling at these early stages of senescence and we link this to the formation of ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. A short ...