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This study provides important insights into the regulation of a retained intron in the mRNA coding for OGT, a process known to be regulated by the O-GlcNAc cycling system, and highlights the ...

Research utilizing AI tool AlphaFold has revealed a new protein complex that initiates the fertilization process between ...

The formation of HIV-induced CPSF6 puncta is critical for restoring HIV-1 nuclear reverse transcription (RT). CPSF6 protein lacking the FG peptide cannot bind to the viral core, thereby failing to ...

Mitochondria and cytoplasm separation, genome extraction and qPCR were used to detect mitochondrial DNA (mtDNA) leakage. Mitochondria ultrastructure was detected by transmission electron microscopy.

Revealing the circuits driving protein gradients. Key cellular processes, such as cell differentiation, rely on protein gradients, i.e. the uneven distribution of proteins within ...

Now, scientists have discovered that human cells are home to their own hidden superheroes, secretly helping us to fight off a ...

Understanding how deletion mutations in mitochondrial DNA contribute to aging can help delay age-related decline in ...

The cytoskeleton of eukaryotic cells is made of filamentous proteins, and it provides mechanical support to the cell and its cytoplasmic constituents. All cytoskeletons consist of three major ...

Protein glycosylation is a fundamental biological process that regulates various cellular functions, yet its study has been hampered by the complexity and low abundance of glycoproteins.