When metabolism of cinacalcet by the cytochrome P450-related liver enzyme CYP3A4 is inhibited by ketoconazole, itraconazole, voriconazole, telithromycin or ritonavir, cinacalcet dose should be ...

Researchers reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected 'second jobs' within the nucleus, orchestrating critical ...

近日，国际权威期刊《 Proceedings of the National Academy of Sciences 》在线发表了武汉大学药学院张郑宇课题组和上海交通大学瞿旭东课题组 、厦门大学王斌举课题组的合作成果，题为 “A nucleobase-driven P450 peroxidase system enables regio- and stereo-specific formation ...