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腾讯网
29 天
二甲双胍作用的直接靶点丨Trends in Endocrinology & Metabolism综述
细胞色素P4503A4(Cytochrome P450 (CYP) 3A4) 在线粒体中,细胞色素P4503A4也被发现可以和二甲双胍结合[7]。CYP3A4在药物和外源性物质的代谢中起着关键作用。
生物通
24 天
PNAS|武汉大学药学院张郑宇课题组与合作者揭示吡咯并吲哚类天然 ...
近日,国际权威期刊《 Proceedings of the National Academy of Sciences 》在线发表了武汉大学药学院张郑宇课题组和上海交通大学瞿旭东课题组 、厦门大学王斌举课题组的合作成果,题为 “A nucleobase-driven P450 peroxidase system enables regio- and stereo-specific formation ...
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