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The EMBO Journal
1 天
Acquired resistance to PD-L1 inhibition enhances a type I IFN-regulated secretory program ...
Acquired resistance to PD-L1 inhibition can rewire the interferon-regulated secretory machinery in tumor cells, altering the ...
GEN
4 天
Lymphoma Immunotherapy Enhanced by Enzyme Inhibitor In Preclinical Model, Prompting Pilot ...
A study in mice offers evidence that inhibiting EZH2 can enhance lymphoma immunogenicity and overcome CAR-T cell therapy resistance.
PharmiWeb
1 天
Bayer starts Phase I study with SOS1 inhibitor in patients with advanced KRAS-mutated tumours
Co-inhibiting SOS1 with KRAS may help to slow or inhibit the growth of cancer cells reliant on this pathway, by enhancing the effectiveness of KRAS inhibition and contributing to deeper and/or ...
Live Science
1 天
New mRNA injection is step forward in 'quest' to find preeclampsia cure
A new mRNA therapy tested in mice may target the root cause of the potentially fatal pregnancy disorder preeclampsia. It's ...
manilatimes
18 小时
XORTX Announces Presentation at the Rare and Genetic Disease Summit
The presentation highlights XORTX recent pioneering discoveries in the field of Autosomal Dominant Polycystic Kidney Disease ...
18 小时
Immuneering Granted FDA Fast Track Designation for IMM-1-104 in Advanced Melanoma
IMM-1-104 has the potential to benefit melanoma patients who have progressed on or are intolerant to immune checkpoint inhibitors -- IMM-1-104 ...
19 小时
Evaxion establishes new AI-derived precision cancer vaccine concept
Evaxion’s AI-Immunology™ platform allows for the design of precision cancer vaccines targeting non-conventional ERV tumor antigens shared across ...
manilatimes
17 小时
Invea Therapeutics Strengthens Leadership with Appointment of Dr. Stephen Doberstein ...
Dr. Doberstein joins a distinguished group of board members with deep expertise in biotechnology, AI-driven drug discovery, ...
Neuroscience News
11 小时
Gut Serotonin Plays Role in Depression and Mood
Serotonin in the gut epithelium plays a critical role in modulating mood and may provide a safer target for treating ...
1 天
NewAmsterdam Pharma: Positive Obicetrapib Data Leads To New Catalysts
NewAmsterdam Pharma's obicetrapib demonstrates strong phase 3 results. Discover why NAMS stock could rise as further studies ...
technologynetworks
1 天
A Novel Class of Antivirals Targets Enzymes Common to Many RNA Viruses
Researchers have introduced a proof-of-concept for a new class of antivirals that could be used against RNA viruses including ...
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