Chromatin is a flexibly joined chain of nucleosomes that exists inside the nucleus of eukaryotic cells and has been described as a 'bead on a string'. Chromatin organization strengthens DNA for ...
Roseman et al. use a new inhibitor of the maintenance DNA methyltransferase DNMT1 to probe the role of methylation on binding of the CTCF protein, which is known to be involved chromatin loop ...
Quickly kick off projects with intelligent suggestions, page templates, and an insert menu at your fingertips to easily add what you need to work together. Let Loop do the searching for you Save time ...
This work will be of high interest to a broad swathe of scientists studying native macromolecules present at low concentrations in cells. Cryo-EM single-particle analyses typically require target ...
So if your Windows computer restarts without warning and goes into a reboot loop here are a few things you could try. Please go through the entire posts first, along with the mentioned links ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Complex transcriptional control is a conserved ...
Cohesin complexes carrying STAG1 or STAG2 organize the genome into chromatin loops. STAG2 loss-of-function mutations promote metastasis in Ewing sarcoma, a pediatric cancer driven by the fusion ...
The London Outer Orbital Path, or LOOP, almost completely encircles Greater London. Nearly 150 miles are split into 24 sections between Erith station and Purfleet. Taking the 150 mile (242km) London ...