Chromatin is a flexibly joined chain of nucleosomes that exists inside the nucleus of eukaryotic cells and has been described as a 'bead on a string'. Chromatin organization strengthens DNA for ...
Eisbach Bio's innovative approach focuses on exploiting the unique genetic vulnerabilities present in solid tumors with deficiencies in certain DNA repair pathways. Eisbach’s proprietary ALLOS ...
Given their non-migratory nature within the mineralized matrix, their unique dendrites are crucial for cell-to-cell communication in response to both intracellular and extracellular stimuli, such as ...
Early development of an embryo is solely supported by maternally deposited RNAs and proteins until its own genome is activated through a process called zygotic genome activation (ZGA).
New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...
Atypical progeria syndromes provide insights into aging and chromatin organization. Here, authors show that a LMNA mutation in mandibuloacral dysplasia disrupt chromatin structure and accelerate ...