Although bronchial hyperresponsiveness to cholinergic agents is a main feature of asthma, the role of anticholinergic drugs in chronic asthma management has been largely underestimated.

Consequently, combination therapy currently involves the administration of one cholinergic drug (donepezil, galantamine or rivastigmine) and one glutamatergic drug (memantine). There have been no ...

Designation underscores significant unmet need in frontotemporal dementia and the potential role of neflamapimod in multiple neurologic ...

Neurones of one system, described and illustrated by us in the rat brain 1,2, contain acetylcholinesterase (AChE) throughout their length and are believed to be cholinergic, releasing ...

The drug has a novel mechanism of action, which is the first for schizophrenia in several decades. Cobenfy targets cholinergic receptors instead of balancing levels of dopamine and serotonin ...

For around 70 years, the treatment of schizophrenia has relied almost entirely on drugs that block dopamine receptors, so Cobenfy's action on cholinergic receptors offers a brand new way to treat ...

The drugs generated about 49% of BMS’ total ... mechanisms while Cobenfy is a first-in-class drug that targets cholinergic receptors. Rather than beginning with major depressive disorders ...

The company told CBS it will charge around $80 for a 30-day supply of Vuity, a once-daily eyedrop formulation of muscarinic cholinergic ... the condition. The drug may find a market among people ...

Neuland Labs share price surged after AbbVie’s emraclidine trial setback shifted focus to KarXT. As the exclusive Xanomaline ...

There are approx. 80+ key companies which are developing the therapies for Dementia Associated With Alzheimer's Disease. The companies which have their Dementia Associated With Alzheimer's Disease ...

Neflamapimod treatment previously led to significant reduction in plasma GFAP levels (p=0.015 versus placebo) and these reductions were associated with an improvement in clinical outcomes The ...

Lewy body disease (LBD), which includes dementia with Lewy bodies (DLB) and Parkinson’s disease with or without dementia, is ...