Toxicity ≥3 or ≥2 according to CTCAE v2.0 Decreased risk of toxicity for the haplotype 677C-1298C in 5-FU + RT-treated patients Higher risk of diarrhea and mucositis in AA homozygotes treated ...
However, it is imperative to carefully balance the risk of toxicity and functional impairment with survival benefit. Differential Effects of Chemotherapy in Elderly Patients Aging is associated ...