In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...
As the body gets older, cells become tired and stop working effectively. This process – called cell senescence – is a common effect of ageing but can also be triggered by diseases at any stage of life ...
When a telomere attains a critical short length, cells recognize it, and replication is attenuated, which results in cell senescence. Previous studies have indicated that magnesium maintains telomeric ...