Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...

Here, we used deep full-length single-cell RNA-sequencing to distinguish post-mitotic cone and rod developmental states and cone-specific features that contribute to retinoblastomagenesis. The ...

The most comprehensive map of the developing human thymus sheds light on how immune responses are built and maintained at early life, with implications for understanding and treating immunodeficiency, ...

Gliocidin selectively kills glioblastoma cells by inhibiting nucleotide synthesis, showing potential as a therapeutic option ...

BPGbio, Inc., a leading biology-first, AI-powered clinical-stage biopharma company focused on mitochondrial biology and protein homeostasis, today announced that it will co-present two pivotal studies ...

The Dallas Stars are holding the team's annual Hockey Fights Cancer night, and they invited a special guest to help them ...

According to a report of The Indian Express, Delhi-based gastroenterologist Dr V.K Gupta has become one of the first patients ...

Daiichi Sankyo (TSE: 4568) will highlight new clinical research and real-world data from seven abstracts for TURALIO ® (pexidartinib) at the Connective Tissue Oncology Society (#CTOS2024) 2024 Annual ...

Cheng Zhu and collaborators probe the underlying mechanisms of PD-1 checkpoint inhibitor therapy and discover the critical ...

In a recent Science article, researchers unveiled a method to kill cancer cells by sticking two proteins together to activate a gene that signals for cell death. This new method is helpful for ...

Beijing Normal University presented data on fibroblast activation protein (FAP)-targeting agents containing a nitroimidazole moiety, [68Ga]/[177Lu]AAZTA-NI-FAPI-04, being developed for the potential ...

Carvykti followed Bristol Myers Squibb and 2Seventy bio’s Abecma onto the market. Like Abecma, it is a CAR-T therapy targeted to a protein called BCMA that’s commonly found on diseased multiple ...