However, on the other hand, they favoured recruitment of beneficial neutrophils through IL-8 secretion and, most importantly, they drove highly cytotoxic CCR5+CCR6+CD8+ T cells into tumour tissue, ...

Neutrophils, monocytes and macrophages arise from common precursors, explaining much of their functional and phenotypical overlap. However, these cells also have complementary functions during the ...

The interaction between myeloid and stromal cells has received considerable attention, but other immune cell infiltrates, such as Tregs, TH2, TH17, and NKT cells, also significantly influence TME ...

Th17 cell differentiation and B cell receptor signaling pathway, were also enriched in wt mice (Fig S3, Table S1). To explore the biological functions of the genes influenced by CD131, we investigated ...

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China ...

1 MRC Centre for Immune Regulation, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK Objectives In rheumatoid arthritis (RA), a ...