Marchetti’s laboratory is penetrating research to improve understandings of mechanisms underlying brain metastasis; this, by capturing changes in the brain microenvironment and investigating ...

This important work substantially advances our understanding of reactive oxygen species (ROS) as a regenerative signal during postnatal cerebellum repair by activating adaptive progenitor ...

Download this application note from 10x Genomics to learn how scientists used a 380-gene immuno-oncology panel to study tumor organization and the tumor microenvironment in ovary, lung, pancreatic, ...

unique brain microenvironment, and subtle changes during metastasis, makes it distinct from primary tumors. A deeper understanding of the biological characteristics and regulatory mechanisms of ...

Researchers have designed process that uses ultrasound to modify the behavior of cancer-fighting T cells by increasing their cell permeability. They targeted freshly isolated human immune cells with ...

Recognizing that brain tumors are ecosystems composed of many different types of cells, we adopted technologies that enable genomic profiling of individual cells, including scRNA-seq and scATAC-seq.

And third, solid tumors in human tissue have a microenvironment that fends off immune system attacks. "Especially in the ...