Our results show that degradation of chondroitin sulfate using chondroitinase ABC can render the environment of the damaged CNS more permissive to axon regeneration. This result confirms that ...

Schwab, previously discovered that neurite growth inhibitors prevent repair and regeneration in the central nervous system (CNS ... Nogo-A as a key inhibitor of axonal growth.

Capitalizing on potent intrinsic transcriptional programs for axon regeneration can provide opportunities for improving peripheral nerve repair and overcoming the permanent loss of function following ...

Our lab is particularly interested in the common underlying mechanisms between axon regeneration and cancer cell migration within the central nervous system. We hypothesize that an exploitation of ...