As shown on the right, TES release the interleukin IL-2, which stimulates CAR-T cells to multiply, and anti-CD3 and anti-CD28, two antibodies that, similar to tumor antigens presented by an ...
Indeed, most monoclonal antibody (mAb) drug discovery projects in I-O are focused on just a few targets, such as the checkpoint molecule programmed cell death 1 and CD19-specific chimeric antigen ...
Illustration of three-step DOTA-PRIT based on targeting with an IgG-scFv bispecific antibody (e.g., huA33-C825 for detection and treatment of colorectal cancer) with dual specificity for a ...
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