Immunotherapies use antibodies—proteins that bind to cell markers called antigens—to target and eliminate the antigen. But despite how effective immunotherapy can be, it isn't widely used ...
Immunological paralysis occurs when one antigenic determinant binds to one receptor antibody on an antigen sensitive cell, whereas induction requires the stretching of that receptor on binding two ...
A Golden Gate-based dual-expression vector enables rapid screening, which facilitates efficient isolation of high-affinity cross-reactive antibodies for therapeutic or diagnostic use and provides a ...
These antibodies are typically detected in ELISA with citrullinated peptides (eg, CCP2) or -proteins as antigens. The absolute concentration of anti-CCP antibodies in serum is unknown. Although ...
In broad terms, these approaches have traditionally included passive and active immunotherapies, whereby cells, antibodies or cytokines ... that can affect T-cell or antigen-presenting cell ...