Morphic had previously also entered into a research collaboration with AbbVie, focusing on alpha V beta 6 integrin inhibitors, but rights to that were returned to the biotech after a safety signal ...
The article, published in Nature Communications, is titled "An engineered AAV targeting integrin alpha V beta 6 presents improved myotropism across species." "The era of gene therapy for ...
They discovered that patients with ulcerative colitis carry autoantibodies that target integrin alpha-v/beta-6, a protein that connects epithelial cells in the intestine to other types of tissue.