A: The first antiviral drug developed for herpes simplex infections was Zovirax (acyclovir). It was first approved in 1982 as a topical cream to treat cold sores. Oral tablets also became ...
Aciclovir or acyclovir is an antiviral agent used to treat cold sores around the mouth caused ... with or without food. It comes as cream, ointment to apply over the affected area.