Other mechanisms include platelet activation with shortening of survival, splenic platelet sequestration and impaired platelet production in the bone marrow. Virus-induced platelet activation and ...

However, the mechanisms that may promote platelet activation and thrombosis during prediabetes have not been studied. We hypothesized that in prediabetes, dysregulation of electron transfer and ...

Despite being acaryote cell fragments, platelets share a number of properties ... attach to them and become activated, thereby releasing the content of their granules. Consequently, antimicrobial ...

Background: Coronary endothelial dysfunction plays a key role in the pathogenesis of cardiovascular events. In the setting of myocardial infarction (MI), activated platelets release prothrombotic and ...

1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Tianjin Key Laboratory of Gene Therapy for Blood Diseases, ...

This new research sheds light on how platelets contribute to the inflammation that fuels plaque formation. The team ...

Figure 1: Targeted disruption of P2y1 locus and aggregation responses of wild-type (WT) and P2y1 –/– platelets. Figure 2: Cellular events in stimulated P2y1 –/– and wild-type platelets.

A low platelet count (thrombocytopenia) means your blood lacks the small cells needed to form clots. Common causes of low platelets include an autoimmune disease called idiopathic thrombocytopenic ...

Pregnancy comes with a lot of risk factors - the deadliest being excessive bleeding following childbirth, also referred to as ...

Of the three ingredients for the ‘incubation mixture’, as originally described, only the preparation of a consistently satisfactory platelet suspension is troublesome and time-consuming enough ...