Hypoxia-driven ... cells is a microenvironment of supporting cells including stromal cells, such as lung fibroblasts, and tissue resident and transient circulating immune cells.

In the tumor microenvironment, macrophages are usually reprogrammed to suppress the immune system, leading to worse outcomes for patients. However, this study found that, when exposed to hypoxia ...

The lack of oxygen and an acidic pH within the tumour are responsible for disarming immune cells, so various nanomedicine strategies have been developed by Liu’s group to relieve tumour hypoxia ...

These factors arise deep within the tumor microenvironment ... roles of deoxyribonucleic acid (DNA) damage, cell clusters, ...

Clinical-stage biotechnology company Halozyme focuses on developing and commercializing cancer therapies that target the tumor microenvironment ... increased hypoxia, decreased immune cell ...