Cells prefer ACLY but, in the event of problems, ACSS2 picks up the slack to ensure a continual supply of acetyl-CoA. Although this type of "metabolic flexibility" has been observed in cancer ...
ACC, acetyl-CoA carboxylase; AMPK ... Cite this: Banting Lecture 2001: Dysregulation of Fatty Acid Metabolism in the Etiology of Type 2 Diabetes - Medscape - Jan 01, 2002.