Ondansetron (as HCl dihydrate) 2mg/mL; IV or IM inj. Ondansetron is a selective 5-HT3 receptor antagonist. Serotonin receptors of the 5-HT3 type are present both peripherally on vagal nerve ...

The plasma half-life of ondansetron is approximately 2.9 hours in volunteers. If these skin-flare data do reflect the duration of blockade of the 5-HT 3 receptor mediating acute emesis in humans ...

Zofran is also considered one of the more effective antiemetics for the treatment ... The active compounds in cannabis, called cannabinoids, work by binding to nerve receptors that "mute" the response ...