Thirty-five elderly patients (mean age 67 years) receiving cardiac home health care and long-term oral anticoagulation were evaluated with paired measurements of the international normalized ratio ...

Vitamin K antagonists, such as warfarin, have an unpredictable pharmacokinetic profile and numerous food and drug interactions, which need frequent monitoring, creating a burden for patients and ...

This should be followed by INR monitoring every two to four weeks during the first two months of combination therapy. Increased prothrombin times induced by combined vitamin E and warfarin therapy ...