However, these data suggest that there may be some abnormality in uric acid metabolism in the heterozygote ... all the clinical manifestations of gout, including hyperuricemia, urinary tract ...

and the generation of uric acid. In this article, we revisit the hypothesis that it is this unique aspect of fructose metabolism that accounts for why fructose intake increases the risk for ...

Disorders of purine metabolism can lead to various health conditions, such as gout, Lesch-Nyhan syndrome, and immunodeficiencies. Gout is a common metabolic disorder characterized by the accumulation ...

An elevated uric acid also independently predicts the development of fatty liver, [41] obesity, [70] hypertension (rev. in, [71] and elevations in C-reactive protein. [72] Furthermore, metabolic ...