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Urea cycle disorder treatment market to hit $215.4m by 2028
It is driven by the increasing prevalence of UCDs. The global urea cycle disorder (UCD) treatment market is projected to grow ...
Cambridge University Press14y
Liver Disease in Children
Marshall L. Summar M.D. The urea cycle was first described in 1932 by Krebs and Henseleit [1] (Figure 36.1). The urea cycle disorders (UCD) result from defects in the metabolism of the extra nitrogen ...
Medscape8d
Not So Rare: Errors of Metabolism During the Neonatal Period
Sandra A. Banta-Wright, MN, RNC, NNP; Robert D. Steiner, MD Neonates with profound and prolonged hyperammonemia with coma due to urea cycle defect will have had a neurological insult to the brain ...
Nature4y
Synlogic probiotics turn up the heat on cancer and metabolic disease
The company’s most advanced candidate therapy, SYNB1020, targets hyperammonemia in individuals born with urea cycle disorders (UCDs). It has been given both Orphan Drug and Fast Track ...